Oestrogen Activates the MAP3K1 Cascade and β-Catenin to Promote Granulosa-like Cell Fate in a Human Testis-Derived Cell Line

Sex determination triggers the differentiation of the bi-potential gonad into either an ovary or testis. In non-mammalian vertebrates, the presence or absence of oestrogen dictates gonad differentiation, while in mammals, this mechanism has been supplanted by the testis-determining gene SRY. Exogeno...

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Detalles Bibliográficos
Autores principales: Stewart, Melanie K., Bernard, Pascal, Ang, Ching-Seng, Mattiske, Deidre M., Pask, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471392/
https://www.ncbi.nlm.nih.gov/pubmed/34576208
http://dx.doi.org/10.3390/ijms221810046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471392/
https://www.ncbi.nlm.nih.gov/pubmed/34576208
http://dx.doi.org/10.3390/ijms221810046

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