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Selective Breeding for Disease-Resistant PRNP Variants to Manage Chronic Wasting Disease in Farmed Whitetail Deer

Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy (TSE) of cervids caused by a misfolded variant of the normal cellular prion protein, and it is closely related to sheep scrapie. Variations in a host’s prion gene, PRNP, and its primary protein structure dramatically af...

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Detalles Bibliográficos
Autores principales: Haley, Nicholas, Donner, Rozalyn, Merrett, Kahla, Miller, Matthew, Senior, Kristen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471411/
https://www.ncbi.nlm.nih.gov/pubmed/34573378
http://dx.doi.org/10.3390/genes12091396