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Selective Breeding for Disease-Resistant PRNP Variants to Manage Chronic Wasting Disease in Farmed Whitetail Deer
Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy (TSE) of cervids caused by a misfolded variant of the normal cellular prion protein, and it is closely related to sheep scrapie. Variations in a host’s prion gene, PRNP, and its primary protein structure dramatically af...
Autores principales: | Haley, Nicholas, Donner, Rozalyn, Merrett, Kahla, Miller, Matthew, Senior, Kristen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471411/ https://www.ncbi.nlm.nih.gov/pubmed/34573378 http://dx.doi.org/10.3390/genes12091396 |
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