Advances in Gene Delivery Methods to Label and Modulate Activity of Upper Motor Neurons: Implications for Amyotrophic Lateral Sclerosis

The selective degeneration of both upper motor neurons (UMNs) and lower motor neurons (LMNs) is the pathological hallmark of amyotrophic lateral sclerosis (ALS). Unlike the simple organisation of LMNs in the brainstem and spinal cord, UMNs are embedded in the complex cytoarchitecture of the primary...

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Detalles Bibliográficos
Autores principales: Haidar, Mouna, Viden, Aida, Turner, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471472/
https://www.ncbi.nlm.nih.gov/pubmed/34573134
http://dx.doi.org/10.3390/brainsci11091112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471472/
https://www.ncbi.nlm.nih.gov/pubmed/34573134
http://dx.doi.org/10.3390/brainsci11091112

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