Activation of Coronary Arteriolar PKCβ2 Impairs Endothelial NO-Mediated Vasodilation: Role of JNK/Rho Kinase Signaling and Xanthine Oxidase Activation

Protein kinase C (PKC) activation can evoke vasoconstriction and contribute to coronary disease. However, it is unclear whether PKC activation, without activating the contractile machinery, can lead to coronary arteriolar dysfunction. The vasoconstriction induced by the PKC activator phorbol 12,13-d...

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Detalles Bibliográficos
Autores principales: Thengchaisri, Naris, Hein, Travis W., Ren, Yi, Kuo, Lih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471475/
https://www.ncbi.nlm.nih.gov/pubmed/34575925
http://dx.doi.org/10.3390/ijms22189763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471475/
https://www.ncbi.nlm.nih.gov/pubmed/34575925
http://dx.doi.org/10.3390/ijms22189763

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