Nivolumab Reduces PD1 Expression and Alters Density and Proliferation of Tumor Infiltrating Immune Cells in a Tissue Slice Culture Model of Renal Cell Carcinoma

SIMPLE SUMMARY: Immune checkpoint inhibitors (ICIs) have become a first-choice therapy option in the treatment of clear cell renal cell carcinoma (ccRCC). A predictive biomarker is urgently needed since not all patients respond and adverse events occur. Therefore, an ex vivo tissue slice culture (TS...

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Detalles Bibliográficos
Autores principales: Stenzel, Philipp J., Hörner, Nina, Foersch, Sebastian, Wagner, Daniel-Christoph, Tsaur, Igor, Thomas, Anita, Haferkamp, Axel, Macher-Goeppinger, Stephan, Roth, Wilfried, Porubsky, Stefan, Tagscherer, Katrin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471479/
https://www.ncbi.nlm.nih.gov/pubmed/34572738
http://dx.doi.org/10.3390/cancers13184511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471479/
https://www.ncbi.nlm.nih.gov/pubmed/34572738
http://dx.doi.org/10.3390/cancers13184511

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