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Neutralizing Concentrations of Anti-Botulinum Toxin Antibodies Positively Correlate with Mouse Neutralization Assay Results in a Guinea Pig Model

Botulinum neurotoxins (BoNT) are some of the most toxic proteins known and can induce respiratory failure requiring long-term intensive care. Treatment of botulism includes the administration of antitoxins. Monoclonal antibodies (mAbs) hold considerable promise as BoNT therapeutics and prophylactics...

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Detalles Bibliográficos
Autores principales: Tomic, Milan T., Farr-Jones, Shauna, Syar, Emily S., Niemuth, Nancy, Kobs, Dean, Hackett, Michael J., Espinoza, Yero, Martinez, Zacchary, Pham, Khanh, Snow, Doris M., Marks, James D., Cobb, Ronald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471557/
https://www.ncbi.nlm.nih.gov/pubmed/34564675
http://dx.doi.org/10.3390/toxins13090671