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Deletion of a Rare Fungal PKS CgPKS11 Promotes Chaetoglobosin A Biosynthesis, Yet Defers the Growth and Development of Chaetomium globosum

We previously reported that chaetoglobosin A (ChA) exhibits a great potential in the biocontrol of nematodes and pathogenic fungi. To improve the production of ChA, a CRISPR-Cas9 system was created and applied for eliminating potential competitive polyketide products. One of the polyketide synthase...

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Detalles Bibliográficos
Autores principales: Xiang, Biyun, Hao, Xiaoran, Xie, Qiaohong, Shen, Guangya, Liu, Yanjie, Zhu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471558/
https://www.ncbi.nlm.nih.gov/pubmed/34575788
http://dx.doi.org/10.3390/jof7090750