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Microdialysis on Ex Vivo Porcine Ear Skin Can Validly Study Dermal Penetration including the Fraction of Transfollicular Penetration—Demonstrated on Caffeine Nanocrystals

Common ex vivo methods for penetration investigations often fail to monitor transfollicular penetration appropriately. In the present investigation, the validity of dermal microdialysis on the ex vivo porcine ear skin to investigate penetration kinetics, including transfollicular penetration, was st...

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Detalles Bibliográficos
Autores principales: Klein, Anna Lena, Lubda, Markus, Specht, David, Pyo, Sung-Min, Busch, Loris, Lademann, Jürgen, Meinke, Martina C., Beckers, Ingeborg, von Hagen, Jörg, Keck, Cornelia M., Patzelt, Alexa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471563/
https://www.ncbi.nlm.nih.gov/pubmed/34578703
http://dx.doi.org/10.3390/nano11092387