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Inducible Pluripotent Stem Cells to Model and Treat Inherited Degenerative Diseases of the Outer Retina: 3D-Organoids Limitations and Bioengineering Solutions

Inherited retinal degenerations (IRD) affecting either photoreceptors or pigment epithelial cells cause progressive visual loss and severe disability, up to complete blindness. Retinal organoids (ROs) technologies opened up the development of human inducible pluripotent stem cells (hiPSC) for diseas...

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Detalles Bibliográficos
Autores principales: Andreazzoli, Massimiliano, Barravecchia, Ivana, De Cesari, Chiara, Angeloni, Debora, Demontis, Gian Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471616/
https://www.ncbi.nlm.nih.gov/pubmed/34572137
http://dx.doi.org/10.3390/cells10092489