Oxidative Stress and Neurodegeneration: Interconnected Processes in PolyQ Diseases

Neurodegenerative polyglutamine (polyQ) disorders are caused by trinucleotide repeat expansions within the coding region of disease-causing genes. PolyQ-expanded proteins undergo conformational changes leading to the formation of protein inclusions which are associated with selective neuronal degene...

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Detalles Bibliográficos
Autores principales: Gkekas, Ioannis, Gioran, Anna, Boziki, Marina Kleopatra, Grigoriadis, Nikolaos, Chondrogianni, Niki, Petrakis, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471619/
https://www.ncbi.nlm.nih.gov/pubmed/34573082
http://dx.doi.org/10.3390/antiox10091450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471619/
https://www.ncbi.nlm.nih.gov/pubmed/34573082
http://dx.doi.org/10.3390/antiox10091450

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