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Betulinic Acid–Doxorubicin-Drug Combination Induced Apoptotic Death via ROS Stimulation in a Relapsed AML MOLM-13 Cell Model

In this study, cell death regulation and induction in AML cell line from a relapsed MLL-rearranged cell model (MOLM-13) was investigated with doxorubin (Dox) and betulinic acid (BetA), singly and in combination. CyQUANT Direct(®) and Annexin V/propidium iodide double staining were used to measure th...

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Detalles Bibliográficos
Autores principales: Vu, Milan, Kassouf, Nick, Appiah, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471649/
https://www.ncbi.nlm.nih.gov/pubmed/34573088
http://dx.doi.org/10.3390/antiox10091456