Systemically Administered Homing Peptide Targets Dystrophic Lesions and Delivers Transforming Growth Factor-β (TGFβ) Inhibitor to Attenuate Murine Muscular Dystrophy Pathology

Muscular dystrophy is a progressively worsening and lethal disease, where accumulation of functionality-impairing fibrosis plays a key pathogenic role. Transforming growth factor-β1 (TGFβ1) is a central signaling molecule in the development of fibrosis in muscular dystrophic humans and mice. Inhibit...

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Detalles Bibliográficos
Autores principales: Iqbal, Aqsa, May, Ulrike, Prince, Stuart N., Järvinen, Tero A.H., Heydemann, Ahlke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471674/
https://www.ncbi.nlm.nih.gov/pubmed/34575582
http://dx.doi.org/10.3390/pharmaceutics13091506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471674/
https://www.ncbi.nlm.nih.gov/pubmed/34575582
http://dx.doi.org/10.3390/pharmaceutics13091506

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