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CSF Secretion Is Not Altered by NKCC1 Nor TRPV4 Antagonism in Healthy Rats

Background: Cerebrospinal fluid (CSF) secretion can be targeted to reduce elevated intracranial pressure (ICP). Sodium-potassium-chloride cotransporter 1 (NKCC1) antagonism is used clinically. However, supporting evidence is limited. The transient receptor potential vanilloid-4 (TRPV4) channel may a...

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Detalles Bibliográficos
Autores principales: Bothwell, Steven W., Omileke, Daniel, Patabendige, Adjanie, Spratt, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471756/
https://www.ncbi.nlm.nih.gov/pubmed/34573139
http://dx.doi.org/10.3390/brainsci11091117