Cargando…

CSF Secretion Is Not Altered by NKCC1 Nor TRPV4 Antagonism in Healthy Rats

Background: Cerebrospinal fluid (CSF) secretion can be targeted to reduce elevated intracranial pressure (ICP). Sodium-potassium-chloride cotransporter 1 (NKCC1) antagonism is used clinically. However, supporting evidence is limited. The transient receptor potential vanilloid-4 (TRPV4) channel may a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bothwell, Steven W., Omileke, Daniel, Patabendige, Adjanie, Spratt, Neil J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471756/ https://www.ncbi.nlm.nih.gov/pubmed/34573139 http://dx.doi.org/10.3390/brainsci11091117

Ejemplares similares

Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia
por: Bothwell, Steven W., et al.
Publicado: (2021)

Short-duration hypothermia completed prior to reperfusion prevents intracranial pressure elevation following ischaemic stroke in rats
por: Omileke, Daniel, et al.
Publicado: (2021)

Decreased Intracranial Pressure Elevation and Cerebrospinal Fluid Outflow Resistance: A Potential Mechanism of Hypothermia Cerebroprotection Following Experimental Stroke
por: Omileke, Daniel, et al.
Publicado: (2021)

Ultra-Short Duration Hypothermia Prevents Intracranial Pressure Elevation Following Ischaemic Stroke in Rats
por: Omileke, Daniel, et al.
Publicado: (2021)

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases
por: Bothwell, Steven William, et al.
Publicado: (2019)

Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1
por: Toft-Bertelsen, Trine L., et al.
Publicado: (2022)

Correction to: A26 Cerebrospinal fluid outflow resistance is increased following small-moderate ischaemic stroke
por: Patabendige, Adjanie, et al.
Publicado: (2019)

Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodynia
por: Pitcher, Mark H, et al.
Publicado: (2007)

Blood–brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?
por: Aryal, Ritambhara, et al.
Publicado: (2021)

Astrocytic aquaporin 4 subcellular translocation as a therapeutic target for cytotoxic edema in ischemic stroke
por: Patabendige, Adjanie, et al.
Publicado: (2022)

The role of the blood–brain barrier during neurological disease and infection
por: Patabendige, Adjanie, et al.
Publicado: (2023)

Editorial: Cerebrospinal fluid dynamics and intracranial pressure elevation–Novel insights on molecular and physiological mechanisms, and implications for neurological disease
por: Patabendige, Adjanie, et al.
Publicado: (2022)

Elevated CSF inflammatory markers in patients with idiopathic normal pressure hydrocephalus do not promote NKCC1 hyperactivity in rat choroid plexus
por: Lolansen, Sara Diana, et al.
Publicado: (2021)

NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension
por: Orlov, Sergei N., et al.
Publicado: (2015)

Establishment of a simplified in vitro porcine blood–brain barrier model with high transendothelial electrical resistance
por: Patabendige, Adjanie, et al.
Publicado: (2013)

Role of SPAK–NKCC1 signaling cascade in the choroid plexus blood–CSF barrier damage after stroke
por: Wang, Jun, et al.
Publicado: (2022)

A detailed method for preparation of a functional and flexible blood–brain barrier model using porcine brain endothelial cells()
por: Patabendige, Adjanie, et al.
Publicado: (2013)

Brain microvascular endothelial-astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood-brain barrier model
por: Patabendige, Adjanie, et al.
Publicado: (2018)

Astrocyte Activation in Neurovascular Damage and Repair Following Ischaemic Stroke
por: Patabendige, Adjanie, et al.
Publicado: (2021)

nor-BNI Antagonism of Kappa Opioid Agonist-Induced Reinstatement of Ethanol-Seeking Behavior
por: Harshberger, Erin, et al.
Publicado: (2016)

Improving NKCC1 Function Increases the Excitability of DRG Neurons Exacerbating Pain Induced After TRPV1 Activation of Primary Sensory Neurons
por: Deng, Shi-Yu, et al.
Publicado: (2021)

Tissue Plasminogen Activator for preclinical stroke research: Neither “rat” nor “human” dose mimics clinical recanalization in a carotid occlusion model
por: Tomkins, Amelia J., et al.
Publicado: (2015)

Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation
por: Koumangoye, Rainelli, et al.
Publicado: (2019)

Inhibition of NKCC1 Attenuated Hippocampal LTP Formation and Inhibitory Avoidance in Rat
por: Ko, Meng Chang, et al.
Publicado: (2014)

Phosphorylation and Transport in the Na-K-2Cl Cotransporters, NKCC1 and NKCC2A, Compared in HEK-293 Cells
por: Hannemann, Anke, et al.
Publicado: (2011)

Acidification of rat TRPV1 alters the kinetics of capsaicin responses
por: Neelands, Torben R, et al.
Publicado: (2005)

Stimulating severe COVID-19: the potential role of GM-CSF antagonism
por: Leavis, Helen L, et al.
Publicado: (2022)

Upregulation of Spinal ASIC1 and NKCC1 Expression Contributes to Chronic Visceral Pain in Rats
por: Li, Yong-Chang, et al.
Publicado: (2021)

NKCC1 and KCC2: Structural insights into phospho-regulation
por: Hartmann, Anna-Maria, et al.
Publicado: (2022)

The subcommissural organ of the rat secretes Reissner's fiber glycoproteins and CSF-soluble proteins reaching the internal and external CSF compartments
por: Vio, Karin, et al.
Publicado: (2008)

Positioning of NORs and NOR-bearing chromosomes in relation to nucleoli
por: Kalmárová, Markéta, et al.
Publicado: (2007)

TRPV1 Antagonism by Capsazepine Modulates Innate Immune Response in Mice Infected with Plasmodium berghei ANKA
por: Fernandes, Elizabeth S., et al.
Publicado: (2014)

Capsazepine antagonizes TRPV1 activation induced by thermal and osmotic stimuli in human odontoblast-like cells
por: Bernal-Cepeda, Lilia Jadith, et al.
Publicado: (2023)

A five amino acids deletion in NKCC2 of C57BL/6 mice affects analysis of NKCC2 phosphorylation but does not impact kidney function
por: Moser, Sandra, et al.
Publicado: (2021)

Gender-Related Effect of Sodium Dichloroacetate on the Number of Hassall's Corpuscles and RNA NKCC1 Expression in Rat Thymus
por: Stanevičiūtė, Jūratė, et al.
Publicado: (2019)

Potassium Channel and NKCC Cotransporter Involvement in Ocular Refractive Control Mechanisms
por: Crewther, Sheila G., et al.
Publicado: (2008)

NKCC1 controls GABAergic signaling and neuroblast migration in the postnatal forebrain
por: Mejia-Gervacio, Sheyla, et al.
Publicado: (2011)

Role of NKCC1 and KCC2 in Epilepsy: From Expression to Function
por: Liu, Ru, et al.
Publicado: (2020)

Capsaicin inhibits intestinal Cl(-) secretion and promotes Na(+) absorption by blocking TRPV4 channels in healthy and colitic mice
por: Wan, Hanxing, et al.
Publicado: (2022)

Pre-eclampsia is associated with altered expression of the renal sodium transporters NKCC2, NCC and ENaC in urinary extracellular vesicles
por: Hu, Chih-Chiang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gtl9s4gjq7ff8s50h000biv6di