Formulation and Bioavailability of Novel Mucoadhesive Buccal Films for Candesartan Cilexetil in Rats

Candesartan cilexetil (CC) is an antihypertensive drug. It has low solubility and faces hepatic first-pass metabolism after oral ingestion. We formulated bioadhesive buccal films and studied the respective drug pharmacokinetics. Different bioadhesive films were prepared (40, 80, 120, 160, 200, and 2...

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Detalles Bibliográficos
Autores principales: Mady, Omar Y., Abulmeaty, Mahmoud M. A., Donia, Ahmed A., Al-Khureif, Abdulaziz A., Al-Shoubki, Adam A., Abudawood, Manal, Abdel Moety, Doaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471814/
https://www.ncbi.nlm.nih.gov/pubmed/34564476
http://dx.doi.org/10.3390/membranes11090659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471814/
https://www.ncbi.nlm.nih.gov/pubmed/34564476
http://dx.doi.org/10.3390/membranes11090659

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