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A Therapeutic Hepatitis B Virus DNA Vaccine Induces Specific Immune Responses in Mice and Non-Human Primates

Despite the availability of an effective prophylactic vaccine for more than 30 years, nearly 300 million people worldwide are chronically infected with the hepatitis B virus (HBV), leading to 1 death every 30 s mainly from viral hepatitis-related cirrhosis and liver cancer. Chronic HBV patients exhi...

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Detalles Bibliográficos
Autores principales: De Pooter, Dorien, Van Gulck, Ellen, Chen, Antony, Evans, Claire F., Neefs, Jean-Marc, Horton, Helen, Boden, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471825/
https://www.ncbi.nlm.nih.gov/pubmed/34579206
http://dx.doi.org/10.3390/vaccines9090969