Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance

SIMPLE SUMMARY: MDM2 is a protein responsible for negative regulation of the p53 tumor suppressor. In addition, MDM2 exhibits chaperone-like properties similar to the HSP90 molecular chaperone. Multiple studies revealed that MDM2 is deeply involved in cancer development and progression. Some recentl...

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Detalles Bibliográficos
Autores principales: Herok, Marcin, Wawrzynow, Bartosz, Maluszek, Marta J., Olszewski, Maciej B., Zylicz, Alicja, Zylicz, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471926/
https://www.ncbi.nlm.nih.gov/pubmed/34572735
http://dx.doi.org/10.3390/cancers13184501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471926/
https://www.ncbi.nlm.nih.gov/pubmed/34572735
http://dx.doi.org/10.3390/cancers13184501

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