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A Preclinical Investigation of GBM-N019 as a Potential Inhibitor of Glioblastoma via Exosomal mTOR/CDK6/STAT3 Signaling

Glioblastoma (GBM) is one of the most aggressive brain malignancies with high incidences of developing treatment resistance, resulting in poor prognoses. Glioma stem cell (GSC)-derived exosomes are important players that contribute to GBM tumorigenesis and aggressive properties. Herein, we investiga...

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Detalles Bibliográficos
Autores principales: Wu, Alexander T. H., Huang, Hsu-Shan, Wen, Ya-Ting, Lawal, Bashir, Mokgautsi, Ntlotlang, Huynh, Thanh-Tuan, Hsiao, Michael, Wei, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471927/
https://www.ncbi.nlm.nih.gov/pubmed/34572040
http://dx.doi.org/10.3390/cells10092391