Gene Expression and Protein Abundance of Hepatic Drug Metabolizing Enzymes in Liver Pathology

Hepatic drug metabolizing enzymes (DMEs) markedly affect drug pharmacokinetics. Because liver diseases may alter enzymatic function and in turn drug handling and clinical efficacy, we investigated DMEs expression in dependence on liver pathology and liver failure state. In 5 liver pathologies (hepat...

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Detalles Bibliográficos
Autores principales: Drozdzik, Marek, Lapczuk-Romanska, Joanna, Wenzel, Christoph, Szelag-Pieniek, Sylwia, Post, Mariola, Skalski, Łukasz, Kurzawski, Mateusz, Oswald, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471929/
https://www.ncbi.nlm.nih.gov/pubmed/34575411
http://dx.doi.org/10.3390/pharmaceutics13091334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471929/
https://www.ncbi.nlm.nih.gov/pubmed/34575411
http://dx.doi.org/10.3390/pharmaceutics13091334

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