Simulation, In Vitro, and In Vivo Cytotoxicity Assessments of Methotrexate-Loaded pH-Responsive Nanocarriers

In this study, pH-responsive niosomal methotrexate (MTX) modified with ergosterol was prepared for potential anticancer application. The prepared formulation had a size of 176.7 ± 3.4 nm, zeta potential of −31.5 ± 2.6 mV, EE% of 76.9 ± 2.5%, and a pH-responsive behavior in two different pHs (5.4 and...

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Detalles Bibliográficos
Autores principales: Barani, Mahmood, Reza Hajinezhad, Mohammad, Sargazi, Saman, Zeeshan, Mahira, Rahdar, Abbas, Pandey, Sadanand, Khatami, Mehrdad, Zargari, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471936/
https://www.ncbi.nlm.nih.gov/pubmed/34578054
http://dx.doi.org/10.3390/polym13183153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471936/
https://www.ncbi.nlm.nih.gov/pubmed/34578054
http://dx.doi.org/10.3390/polym13183153

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