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EPIsHilbert: Prediction of Enhancer-Promoter Interactions via Hilbert Curve Encoding and Transfer Learning

Enhancer-promoter interactions (EPIs) play a significant role in the regulation of gene transcription. However, enhancers may not necessarily interact with the closest promoters, but with distant promoters via chromatin looping. Considering the spatial position relationship between enhancers and the...

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Detalles Bibliográficos
Autores principales: Zhang, Mingyang, Hu, Yujia, Zhu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472018/
https://www.ncbi.nlm.nih.gov/pubmed/34573367
http://dx.doi.org/10.3390/genes12091385