Neuroprotective Effect of a Novel ATP-Synthase Inhibitor Bedaquiline in Cerebral Ischemia-Reperfusion Injury

Mitochondrial dysfunction during ischemic stroke ultimately manifests as ATP depletion. Mitochondrial ATP synthase upon loss of mitochondrial membrane potential during ischemia rapidly hydrolyses ATP and thus contributes to ATP depletion. Increasing evidence suggests that inhibition of ATP synthase...

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Detalles Bibliográficos
Autores principales: Umbrasas, Danielius, Arandarcikaite, Odeta, Grigaleviciute, Ramune, Stakauskas, Rimantas, Borutaite, Vilmante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472139/
https://www.ncbi.nlm.nih.gov/pubmed/34575875
http://dx.doi.org/10.3390/ijms22189717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472139/
https://www.ncbi.nlm.nih.gov/pubmed/34575875
http://dx.doi.org/10.3390/ijms22189717

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