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Effect of Strain Rate on Single Tau, Dimerized Tau and Tau-Microtubule Interface: A Molecular Dynamics Simulation Study

Microtubule-associated protein (MAP) tau is a cross-linking molecule that provides structural stability to axonal microtubules (MT). It is considered a potential biomarker for Alzheimer’s disease (AD), dementia, and other neurological disorders. It is also a signature protein for Traumatic Brain Inj...

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Detalles Bibliográficos
Autores principales: Khan, Md Ishak, Gilpin, Kathleen, Hasan, Fuad, Mahmud, Khandakar Abu Hasan Al, Adnan, Ashfaq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472149/
https://www.ncbi.nlm.nih.gov/pubmed/34572521
http://dx.doi.org/10.3390/biom11091308