Metabolomic Fingerprint of Mecp2-Deficient Mouse Cortex: Evidence for a Pronounced Multi-Facetted Metabolic Component in Rett Syndrome

Using unsupervised metabolomics, we defined the complex metabolic conditions in the cortex of a mouse model of Rett syndrome (RTT). RTT, which represents a cause of mental and cognitive disabilities in females, results in profound cognitive impairment with autistic features, motor disabilities, seiz...

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Detalles Bibliográficos
Autores principales: Golubiani, Gocha, Lagani, Vincenzo, Solomonia, Revaz, Müller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472238/
https://www.ncbi.nlm.nih.gov/pubmed/34572143
http://dx.doi.org/10.3390/cells10092494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472238/
https://www.ncbi.nlm.nih.gov/pubmed/34572143
http://dx.doi.org/10.3390/cells10092494

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