Betulinic Acid Decorated with Polar Groups and Blue Emitting BODIPY Dye: Synthesis, Cytotoxicity, Cell-Cycle Analysis and Anti-HIV Profiling

Betulinic acid (BA) is a potent triterpene, which has shown promising potential in cancer and HIV-1 treatment. Here, we report a synthesis and biological evaluation of 17 new compounds, including BODIPY labelled analogues derived from BA. The analogues terminated by amino moiety showed increased cyt...

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Detalles Bibliográficos
Autores principales: Kodr, David, Stanková, Jarmila, Rumlová, Michaela, Džubák, Petr, Řehulka, Jiří, Zimmermann, Tomáš, Křížová, Ivana, Gurská, Soňa, Hajdúch, Marián, Drašar, Pavel B., Jurášek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472287/
https://www.ncbi.nlm.nih.gov/pubmed/34572290
http://dx.doi.org/10.3390/biomedicines9091104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472287/
https://www.ncbi.nlm.nih.gov/pubmed/34572290
http://dx.doi.org/10.3390/biomedicines9091104

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