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Co-Treatment with the Epigenetic Drug, 3-Deazaneplanocin A (DZNep) and Cisplatin after DZNep Priming Enhances the Response to Platinum-Based Therapy in Chondrosarcomas

SIMPLE SUMMARY: Chondrosarcoma is a rare bone tumor characterized by the secretion of a cartilage-like extracellular matrix. Its treatment poses major challenges, since chondrosarcoma is resistant to chemotherapy and radiotherapy. Consequently, chondrosarcoma treatment has been limited over the past...

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Detalles Bibliográficos
Autores principales: Lhuissier, Eva, Aury-Landas, Juliette, Lenté, Marion, Boumediene, Karim, Baugé, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472299/
https://www.ncbi.nlm.nih.gov/pubmed/34572877
http://dx.doi.org/10.3390/cancers13184648