Stemness of Human Pluripotent Cells: Hypoxia-Like Response Induced by Low Nitric Oxide

The optimization of conditions to promote the stemness of pluripotent cells in vitro is instrumental for their use in advanced therapies. We show here that exposure of human iPSCs and human ESCs to low concentrations of the chemical NO donor DETA/NO leads to stabilization of hypoxia-inducible factor...

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Detalles Bibliográficos
Autores principales: Caballano-Infantes, Estefanía, Díaz, Irene, Hitos, Ana Belén, Cahuana, Gladys Margot, Martínez-Ruiz, Antonio, Soria-Juan, Bárbara, Rodríguez-Griñolo, Rosario, Hmadcha, Abdelkrim, Martín, Franz, Soria, Bernat, Tejedo, Juan R., Bedoya, Francisco Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472328/
https://www.ncbi.nlm.nih.gov/pubmed/34573040
http://dx.doi.org/10.3390/antiox10091408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472328/
https://www.ncbi.nlm.nih.gov/pubmed/34573040
http://dx.doi.org/10.3390/antiox10091408

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