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HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells

During type 1 diabetes mellitus (T1DM) development, beta-cells undergo intense endoplasmic reticulum (ER) stress that could result in apoptosis through the failure of adaptation to the unfolded protein response (UPR). Islet transplantation is considered an attractive alternative among beta-cell repl...

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Detalles Bibliográficos
Autores principales: Gomes, Vinícius M., Wailemann, Rosangela A. M., Arini, Gabriel S., Oliveira, Talita C., Almeida, Daria R. Q., dos Santos, Ancély F., Terra, Letícia F., Lortz, Stephan, Labriola, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472426/
https://www.ncbi.nlm.nih.gov/pubmed/34571827
http://dx.doi.org/10.3390/cells10092178