HIF-1-Independent Mechanisms Regulating Metabolic Adaptation in Hypoxic Cancer Cells

In solid tumours, cancer cells exist within hypoxic microenvironments, and their metabolic adaptation to this hypoxia is driven by HIF-1 transcription factor, which is overexpressed in a broad range of human cancers. HIF inhibitors are under pre-clinical investigation and clinical trials, but there...

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Detalles Bibliográficos
Autores principales: Lee, Shen-Han, Golinska, Monika, Griffiths, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472468/
https://www.ncbi.nlm.nih.gov/pubmed/34572020
http://dx.doi.org/10.3390/cells10092371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472468/
https://www.ncbi.nlm.nih.gov/pubmed/34572020
http://dx.doi.org/10.3390/cells10092371

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