Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies

Suitable ex vivo models are required as predictive tools of oromucosal permeability between in vitro characterizations and in vivo studies in order to support the development of novel intraoral formulations. To counter a lack of clinical relevance and observed method heterogenicity, a standardized,...

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Detalles Bibliográficos
Autores principales: Majid, Haidara, Puzik, Andreas, Maier, Tanja, Merk, Raphaela, Bartel, Anke, Mueller, Hans-Christian, Burckhardt, Bjoern B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472530/
https://www.ncbi.nlm.nih.gov/pubmed/34575485
http://dx.doi.org/10.3390/pharmaceutics13091409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472530/
https://www.ncbi.nlm.nih.gov/pubmed/34575485
http://dx.doi.org/10.3390/pharmaceutics13091409

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