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Impact of G-Quadruplexes on the Regulation of Genome Integrity, DNA Damage and Repair

DNA G-quadruplexes (G4s) are known to be an integral part of the complex regulatory systems in both normal and pathological cells. At the same time, the ability of G4s to impede DNA replication plays a critical role in genome integrity. This review summarizes the results of recent studies of G4-medi...

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Detalles Bibliográficos
Autores principales: Pavlova, Anzhela V., Kubareva, Elena A., Monakhova, Mayya V., Zvereva, Maria I., Dolinnaya, Nina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472537/
https://www.ncbi.nlm.nih.gov/pubmed/34572497
http://dx.doi.org/10.3390/biom11091284