Neurosteroids: Structure-Uptake Relationships and Computational Modeling of Organic Anion Transporting Polypeptides (OATP)1A2

In this study, we investigated the delivery of synthetic neurosteroids into MCF-7 human breast adenocarcinoma cells via Organic Anionic Transporting Polypeptides (OATPs) (pH 7.4 and 5.5) to identify the structural components required for OATP-mediated cellular uptake and to get insight into brain dr...

Descripción completa

Detalles Bibliográficos
Autores principales: Adla, Santosh Kumar, Tonduru, Arun Kumar, Kronenberger, Thales, Kudova, Eva, Poso, Antti, Huttunen, Kristiina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472597/
https://www.ncbi.nlm.nih.gov/pubmed/34577133
http://dx.doi.org/10.3390/molecules26185662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472597/
https://www.ncbi.nlm.nih.gov/pubmed/34577133
http://dx.doi.org/10.3390/molecules26185662

Ejemplares similares