Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals

High levels of anti-citrullinated protein antibodies (ACPA) are often observed prior to a diagnosis of rheumatoid arthritis (RA). We undertook a replication study to confirm CpG sites showing evidence of differential methylation in subjects positive vs. negative for ACPA, in a new subset of 112 indi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Yixiao, Zhao, Kaiqiong, Oros Klein, Kathleen, Shao, Xiaojian, Fritzler, Marvin J., Hudson, Marie, Colmegna, Inés, Pastinen, Tomi, Bernatsky, Sasha, Greenwood, Celia M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472734/
https://www.ncbi.nlm.nih.gov/pubmed/34573331
http://dx.doi.org/10.3390/genes12091349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472734/
https://www.ncbi.nlm.nih.gov/pubmed/34573331
http://dx.doi.org/10.3390/genes12091349

Ejemplares similares