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Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals
High levels of anti-citrullinated protein antibodies (ACPA) are often observed prior to a diagnosis of rheumatoid arthritis (RA). We undertook a replication study to confirm CpG sites showing evidence of differential methylation in subjects positive vs. negative for ACPA, in a new subset of 112 indi...
Autores principales: | Zeng, Yixiao, Zhao, Kaiqiong, Oros Klein, Kathleen, Shao, Xiaojian, Fritzler, Marvin J., Hudson, Marie, Colmegna, Inés, Pastinen, Tomi, Bernatsky, Sasha, Greenwood, Celia M. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472734/ https://www.ncbi.nlm.nih.gov/pubmed/34573331 http://dx.doi.org/10.3390/genes12091349 |
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