NADPH-Oxidase, Rho-Kinase and Autophagy Mediate the (Pro)renin-Induced Pro-Inflammatory Microglial Response and Enhancement of Dopaminergic Neuron Death

Dysregulation of the tissue renin–angiotensin system (RAS) is involved in tissue oxidative and inflammatory responses. Among RAS components, renin, its precursor (pro)renin and its specific receptor (PRR) have been less investigated, particularly in the brain. We previously showed the presence of PR...

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Detalles Bibliográficos
Autores principales: Lopez-Lopez, Andrea, Villar-Cheda, Begoña, Quijano, Aloia, Garrido-Gil, Pablo, Garcia-Garrote, María, Díaz-Ruiz, Carmen, Muñoz, Ana, Labandeira-Garcia, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472832/
https://www.ncbi.nlm.nih.gov/pubmed/34572972
http://dx.doi.org/10.3390/antiox10091340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472832/
https://www.ncbi.nlm.nih.gov/pubmed/34572972
http://dx.doi.org/10.3390/antiox10091340

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