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NADPH-Oxidase, Rho-Kinase and Autophagy Mediate the (Pro)renin-Induced Pro-Inflammatory Microglial Response and Enhancement of Dopaminergic Neuron Death
Dysregulation of the tissue renin–angiotensin system (RAS) is involved in tissue oxidative and inflammatory responses. Among RAS components, renin, its precursor (pro)renin and its specific receptor (PRR) have been less investigated, particularly in the brain. We previously showed the presence of PR...
Autores principales: | Lopez-Lopez, Andrea, Villar-Cheda, Begoña, Quijano, Aloia, Garrido-Gil, Pablo, Garcia-Garrote, María, Díaz-Ruiz, Carmen, Muñoz, Ana, Labandeira-Garcia, José L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472832/ https://www.ncbi.nlm.nih.gov/pubmed/34572972 http://dx.doi.org/10.3390/antiox10091340 |
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