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Rationally repurposed nitroxoline inhibits preclinical models of Epstein–Barr virus-associated lymphoproliferation

Repurposing of currently used drugs for new indications benefits from known experience with those agents. Rational repurposing can be achieved when newly uncovered molecular activities are leveraged against diseases that utilize those mechanisms. Nitroxoline is an antibiotic with metal-chelating act...

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Detalles Bibliográficos
Autores principales: Ibáñez de Garayo, Maite, Liu, Wendi, Rondeau, Nicole C., Damoci, Christopher B., Miranda, JJ L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472899/
https://www.ncbi.nlm.nih.gov/pubmed/34163027
http://dx.doi.org/10.1038/s41429-021-00433-2