Incorporating the Cluster A and V1V2 Targets into a Minimal Structural Unit of the HIV-1 Envelope to Elicit a Cross-Clade Response with Potent Fc-Effector Functions

The generation of a potent vaccine for the prevention and/or control of HIV-1 has been unsuccessful to date, despite decades of research. Existing evidence from both infected individuals and clinical trials support a role for non-neutralizing or weakly neutralizing antibodies with potent Fc-effector...

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Detalles Bibliográficos
Autores principales: Sherburn, Rebekah, Tolbert, William D., Gottumukkala, Suneetha, Hederman, Andrew P., Beaudoin-Bussières, Guillaume, Stanfield-Oakley, Sherry, Tuyishime, Marina, Ferrari, Guido, Finzi, Andrés, Ackerman, Margaret E., Pazgier, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472903/
https://www.ncbi.nlm.nih.gov/pubmed/34579212
http://dx.doi.org/10.3390/vaccines9090975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472903/
https://www.ncbi.nlm.nih.gov/pubmed/34579212
http://dx.doi.org/10.3390/vaccines9090975

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