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Incorporating the Cluster A and V1V2 Targets into a Minimal Structural Unit of the HIV-1 Envelope to Elicit a Cross-Clade Response with Potent Fc-Effector Functions
The generation of a potent vaccine for the prevention and/or control of HIV-1 has been unsuccessful to date, despite decades of research. Existing evidence from both infected individuals and clinical trials support a role for non-neutralizing or weakly neutralizing antibodies with potent Fc-effector...
Autores principales: | Sherburn, Rebekah, Tolbert, William D., Gottumukkala, Suneetha, Hederman, Andrew P., Beaudoin-Bussières, Guillaume, Stanfield-Oakley, Sherry, Tuyishime, Marina, Ferrari, Guido, Finzi, Andrés, Ackerman, Margaret E., Pazgier, Marzena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472903/ https://www.ncbi.nlm.nih.gov/pubmed/34579212 http://dx.doi.org/10.3390/vaccines9090975 |
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