A Bioluminescent 3CL(Pro) Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors

Our therapeutic arsenal against viruses is very limited and the current pandemic of SARS-CoV-2 highlights the critical need for effective antivirals against emerging coronaviruses. Cellular assays allowing a precise quantification of viral replication in high-throughput experimental settings are ess...

Descripción completa

Detalles Bibliográficos
Autores principales: Mathieu, Cyrille, Touret, Franck, Jacquemin, Clémence, Janin, Yves L., Nougairède, Antoine, Brailly, Manon, Mazelier, Magalie, Décimo, Didier, Vasseur, Virginie, Hans, Aymeric, Valle-Casuso, José-Carlos, de Lamballerie, Xavier, Horvat, Branka, André, Patrice, Si-Tahar, Mustapha, Lotteau, Vincent, Vidalain, Pierre-Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473059/
https://www.ncbi.nlm.nih.gov/pubmed/34578395
http://dx.doi.org/10.3390/v13091814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473059/
https://www.ncbi.nlm.nih.gov/pubmed/34578395
http://dx.doi.org/10.3390/v13091814

Ejemplares similares