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A Bioluminescent 3CL(Pro) Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors

Our therapeutic arsenal against viruses is very limited and the current pandemic of SARS-CoV-2 highlights the critical need for effective antivirals against emerging coronaviruses. Cellular assays allowing a precise quantification of viral replication in high-throughput experimental settings are ess...

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Detalles Bibliográficos
Autores principales:	Mathieu, Cyrille, Touret, Franck, Jacquemin, Clémence, Janin, Yves L., Nougairède, Antoine, Brailly, Manon, Mazelier, Magalie, Décimo, Didier, Vasseur, Virginie, Hans, Aymeric, Valle-Casuso, José-Carlos, de Lamballerie, Xavier, Horvat, Branka, André, Patrice, Si-Tahar, Mustapha, Lotteau, Vincent, Vidalain, Pierre-Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473059/ https://www.ncbi.nlm.nih.gov/pubmed/34578395 http://dx.doi.org/10.3390/v13091814

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