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Neutrophil Extracellular Traps Augmented Alveolar Macrophage Pyroptosis via AIM2 Inflammasome Activation in LPS-Induced ALI/ARDS

BACKGROUND: Uncontrollable inflammation is a critical feature of gram-negative bacterial pneumonia-induced acute respiratory distress syndrome (ARDS). Both neutrophils and alveolar macrophages participate in inflammation, but how their interaction augments inflammation and triggers ARDS is unclear....

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Detalles Bibliográficos
Autores principales: Li, Haitao, Li, Yi, Song, Chao, Hu, Yongbin, Dai, Minhui, Liu, Ben, Pan, Pinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473117/
https://www.ncbi.nlm.nih.gov/pubmed/34588792
http://dx.doi.org/10.2147/JIR.S321513