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Alterations in Brain Cannabinoid Receptor Levels Are Associated with HIV-Associated Neurocognitive Disorders in the ART Era: Implications for Therapeutic Strategies Targeting the Endocannabinoid System

HIV-associated neurocognitive disorders (HAND) persist despite the advent of antiretroviral therapy (ART), suggesting underlying systemic and central nervous system (CNS) inflammatory mechanisms. The endogenous cannabinoid receptors 1 and 2 (CB(1) and CB(2)) modulate inflammatory gene expression and...

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Detalles Bibliográficos
Autores principales: Swinton, Mary K., Sundermann, Erin E., Pedersen, Lauren, Nguyen, Jacques D., Grelotti, David J., Taffe, Michael A., Iudicello, Jennifer E., Fields, Jerel Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473156/
https://www.ncbi.nlm.nih.gov/pubmed/34578323
http://dx.doi.org/10.3390/v13091742