The Clonal Expansion Dynamics of the HIV-1 Reservoir: Mechanisms of Integration Site-Dependent Proliferation and HIV-1 Persistence

More than 50% of the HIV-1 latent reservoir is maintained by clonal expansion. The clonally expanded HIV-1-infected cells can contribute to persistent nonsuppressible low-level viremia and viral rebound. HIV-1 integration site and proviral genome landscape profiling reveals the clonal expansion dyna...

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Detalles Bibliográficos
Autores principales: Yeh, Yang-Hui Jimmy, Yang, Kerui, Razmi, Anya, Ho, Ya-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473165/
https://www.ncbi.nlm.nih.gov/pubmed/34578439
http://dx.doi.org/10.3390/v13091858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473165/
https://www.ncbi.nlm.nih.gov/pubmed/34578439
http://dx.doi.org/10.3390/v13091858

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