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Inhibition of MAVS Aggregation-Mediated Type-I Interferon Signaling by Foot-and-Mouth Disease Virus VP3

As a structural protein of the Foot-and-mouth disease virus (FMDV), VP3 plays a vital role in virus assembly and inhibiting the interferon (IFN) signal transduction to promote FMDV replication. Previous studies demonstrated that FMDV VP3 blocks the type-I IFN response by inhibiting the mRNA expressi...

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Detalles Bibliográficos
Autores principales: Ekanayaka, Pathum, Lee, Byeong-Hoon, Weerawardhana, Asela, Chathuranga, Kiramage, Park, Jong-Hyeon, Lee, Jong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473216/
https://www.ncbi.nlm.nih.gov/pubmed/34578357
http://dx.doi.org/10.3390/v13091776