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A Review of the Multipronged Attack of Herpes Simplex Virus 1 on the Host Transcriptional Machinery
During lytic infection, herpes simplex virus (HSV) 1 induces a rapid shutoff of host RNA synthesis while redirecting transcriptional machinery to viral genes. In addition to being a major human pathogen, there is burgeoning clinical interest in HSV as a vector in gene delivery and oncolytic therapie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473234/ https://www.ncbi.nlm.nih.gov/pubmed/34578417 http://dx.doi.org/10.3390/v13091836 |