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A Review of the Multipronged Attack of Herpes Simplex Virus 1 on the Host Transcriptional Machinery

During lytic infection, herpes simplex virus (HSV) 1 induces a rapid shutoff of host RNA synthesis while redirecting transcriptional machinery to viral genes. In addition to being a major human pathogen, there is burgeoning clinical interest in HSV as a vector in gene delivery and oncolytic therapie...

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Detalles Bibliográficos
Autores principales: Hennig, Thomas, Djakovic, Lara, Dölken, Lars, Whisnant, Adam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473234/
https://www.ncbi.nlm.nih.gov/pubmed/34578417
http://dx.doi.org/10.3390/v13091836