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A Review of the Multipronged Attack of Herpes Simplex Virus 1 on the Host Transcriptional Machinery

During lytic infection, herpes simplex virus (HSV) 1 induces a rapid shutoff of host RNA synthesis while redirecting transcriptional machinery to viral genes. In addition to being a major human pathogen, there is burgeoning clinical interest in HSV as a vector in gene delivery and oncolytic therapie...

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Detalles Bibliográficos
Autores principales:	Hennig, Thomas, Djakovic, Lara, Dölken, Lars, Whisnant, Adam W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473234/ https://www.ncbi.nlm.nih.gov/pubmed/34578417 http://dx.doi.org/10.3390/v13091836

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