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Peptide Derivatives of Platelet-Derived Growth Factor Receptor Alpha Inhibit Cell-Associated Spread of Human Cytomegalovirus

Cell-free human cytomegalovirus (HCMV) can be inhibited by a soluble form of the cellular HCMV-receptor PDGFRα, resembling neutralization by antibodies. The cell-associated growth of recent HCMV isolates, however, is resistant against antibodies. We investigated whether PDGFRα-derivatives can inhibi...

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Detalles Bibliográficos
Autores principales: Braun, Berenike, Fischer, Dina, Laib Sampaio, Kerstin, Mezger, Maja, Stöhr, Dagmar, Stanton, Richard James, Sinzger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473290/
https://www.ncbi.nlm.nih.gov/pubmed/34578361
http://dx.doi.org/10.3390/v13091780